The mission of the Center for Mucosal and Microbiome Biology (CMMB) is to support the advancement of microbiome research and education at UTHSA with the ultimate goal of translating discoveries in this field into innovative diagnostics and therapeutics that save lives. The center aims to bolster collaboration between investigators, creating research infrastructure support, enhancing trainee development, and assisting in the recruitment of new faculty with an outstanding track record of research in the fields of microbiome and mucosal biology. From basic science to clinical trials, research at the Center for Mucosal & Microbiome Biology will focus on the cellular and molecular mechanisms involved in the interface between the microbiome and the mucosa, with the primary aim of identifying unique therapeutic platforms and bio-marker signatures to reduce morbidity and mortality from metabolic, infectious, and inflammatory diseases.
Mucosae have complex biological responses to harmful stimuli that are regulated in part by the microbiome; therefore, an interdisciplinary collaborative effort is critical to fully understand its molecular pathogenesis. Understanding these cellular and molecular regulatory mechanisms of the mucosal-microbiome interface will lead to the development of novel anti-inflammatory strategies and accelerate the successful establishment of cutting-edge therapeutic approaches for future clinical trials.