Center for Mucosal & Microbiome Biology
From basic science to clinical trials: spearheading research and educational initiatives focused on the role of the microbiome and the associated metabolites in health and diseases.
CMMB sits on the cutting edge of microbiome research and education at UTHSA, serving as an intellectual nexus for basic and translational immunology.
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Center for Mucosal & Microbiome Biology
The mission of the Center for Mucosal and Microbiome Biology (CMMB) is to support the advancement of microbiome research and education at UTHSA with the ultimate goal of translating discoveries in this field into innovative diagnostics and therapeutics that save lives. The center aims to bolster collaboration between investigators, creating research infrastructure support, enhancing trainee development, and assisting in the recruitment of new faculty with an outstanding track record of research in the fields of microbiome and mucosal biology. From basic science to clinical trials, research at the Center for Mucosal & Microbiome Biology will focus on the cellular and molecular mechanisms involved in the interface between the microbiome and the mucosa, with the primary aim of identifying unique therapeutic platforms and bio-marker signatures to reduce morbidity and mortality from metabolic, infectious, and inflammatory diseases.
Mucosae have complex biological responses to harmful stimuli that are regulated in part by the microbiome; therefore, an interdisciplinary collaborative effort is critical to fully understand its molecular pathogenesis. Understanding these cellular and molecular regulatory mechanisms of the mucosal-microbiome interface will lead to the development of novel anti-inflammatory strategies and accelerate the successful establishment of cutting-edge therapeutic approaches for future clinical trials.
Center for Mucosal & Microbiome Biology
The Center for Mucosal & Microbiome Biology is focused on bolstering the curriculum at UTHSCSA. We are currently developing the following courses.
The field of microbiome is rapidly expanding in both basic and clinical scientific research. Whether in the gut or oral cavity, the microbiome and the associated metabolites play an integral role in human health and can significantly affect disease outcomes. This course will provide an overview on the role of the microbiome and the associated metabolites in human health and disease. It will focus on clarifying the conceptual framework for understanding how microbiome, particularly gut microbiome, impact on human health and well-being. The course will also introduce students to the technical approaches and bioinformatics required to study the microbiome and the associated metabolites in the hosts.
Topics covered include:
Center for Mucosal & Microbiome Biology
The Center for Mucosal & Microbiome Biology specializes in the use of Multiomic Approaches to create a comprehensive picture of the complex interplay between the microbiome and human health. Multiomics is a new approach to biological analysis where data sets of different omics groups (transcriptome, metabolome, etc.) are combined to create a thorough biological analysis.
The applications for multiomics are vast, ranging from elucidating the nature of host-pathogen interactions to illuminating the mechanisms behind non-communicable diseases. By combining these various "omic" approaches, scientists can analyze complex biological data to determine novel associations between biological entities, identify important biomarkers and build elaborate markers of disease and physiology.
The Center utilizes & and will train faculty in the following areas of multiomics:
Center for Mucosal & Microbiome Biology